According to The Wrap , the villain that Rhys Ifans will be playing in Sony/Columbia’s SPIDER-MAN reboot is Dr. Curt Connors — The Lizard.
Dylan Baker played Dr. Connors in SPIDER-MAN 2 and 3, as a sympathetic professor to Peter Parker, presumably before his experiments to regrow his missing arm.
In the original comics, Spider-Man discovers the Lizard in Florida when Peter Parker goes to investigate the case for The Daily Bugle. He uses Connors’ notes to affect an at least temporary cure for the condition, though he would sometime relapse back into his bipedal reptile form.
